Aim: Neurotrauma accounts for a significant amount of death and disability worldwide and the majority of this burden affects individuals in lowandmiddle income countries. Despite this, considerable geographical differences have been reported in the care of patient following neurotrauma. On this background, we aim to provide a comprehensive international picture of the management and outcomes of patients undergoing emergency cranial surgery after traumatic brain injury (TBI) worldwide.
Design: Multicentre, international, prospective cohort study. Each participating unit will form a designated study team responsible for gaining local approval, identifying patients and conducting data collection. Data will be collected via a secure online platform in anonymised form.
Patients: Any unit performing emergency cranial surgery for traumatic brain injury worldwide will be eligible to participate. All TBI patients who receive emergency cranial surgery in any given consecutive 1month period between 1st of January 2018 and 30th of June 2018 in a given participating unit will be included.
Outcomes: Data related to initial presentation, operative intervention and shortterm outcomes will be a collected. The 30item dataset developed through iterative feedback includes patient demographics, details of injury mechanism, timing and nature of surgery, and immediate postoperative complications. The primary outcome measures for the study will be 14day mortality and discharge destination.
Conclusions: The GNOS1 study aims to provide a global picture of the management and outcomes of patients undergoing emergency cranial surgery following TBI. In addition, this will establish a platform and clinical network facilitate future research in global neurotrauma.